Medical Math Question About Alcoholism Please answer the attached question and show your work! 5
OD is a 58-year-old, 80-kg male. He admits to a social history of 3-5
alcoholic drinks per day. Using the appropriate Michaelis-Menten
values in the table below, compute the phenytoin dose that would
achieve Css = 15 mg/L. How does this compare to a Pt that does
not drink alcohol?
Km of patients who do not
consume alcohol was 16.1 mg/L
Km of patients who consume
alcohol was 23.6 mg/L
Vmax of patients who do not
consume alcohol was 649 mg/d
Vmax of patients who consume
alcohol was 260 mg/d
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