Disease and Pathophysiology 1 Changes in the anatomy of small intestines (flat mucosa with villus atrophy, and hyper plastic crypts) The results show that the small intestines are damaged and that their anatomy has changed with regard to the key functions which are digestion and absorption of certain nutrients; the surface area is reduced leading to malabsorption (Marks) 2 Etiology of celiac disease, is Mrs. Gainess history typical of patients with celiac disease? Explain Mrs Gaines history is typical of patients with celiac disease largely because the fact that her siblings and parents experience similar symptoms of celiac disease implying that their genetic make-up is susceptible and hence favorable for development of celiac disease. Celiac disease symptoms such as diarrhea and weight loss tend to increase with increased exposure to the causal factor (s) which in this case is gluten and Mrs. Aines has been experiencing the same over a long period because she didnt refrain from foods containing gluten.
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