You are interested in knowing whether or not indoor radon exposure is associated with lung cancer. You design a __________ study consisting of patients with lung cancer and neighborhood matched controls. You then collected radon levels in the households of each case and control and classify the level as elevated or not elevated according to a standard definition. A. What type of study design is this? B. What measure of association would you use?
Question 2
In a ________ study, investigators compared the effect of pentoxifylline versus placebo on survival in patients with HIV/AIDS who were also treated with standard antiretroviral therapy? A. What type of study design is this? B. What measure of association would you use?
Question 3
In studying coffee and pancreatic cancer, you discover that coffee is associated with an increased risk for pancreatic cancer. During the study, you also collected information about cigarette use, alcohol use, and vitamin use. A. What type of study design is this? B. What measure of association would you use? C. Would you be content to report the information as valid? If not, why not?
Question 4
In a _______ study of women 45 65 years old, you intend to study the risk for coronary heart disease. After a detailed intake interview and examination that included an electrocardiogram and echocardiography, you enroll women without evidence for coronary artery disease. Your hypothesis is that women who eat fish are less likely to develop coronary heart disease as indicated by heart attack. A. What type of study design is this? B. What measure of association would you use?
Question 5
In traditional case- control studies, why is the odds ratio used instead of a relative risk? Hint: Can incidence be measured in a case- control design?
Question 6
Is it possible to conduct a retrospective randomized clinical trial? Briefly explain your answer.
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